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Fig. 1 | BMC Biotechnology

Fig. 1

From: Novel anti-CD38 humanized mAb SG003 possessed enhanced cytotoxicity in lymphoma than Daratumumab via antibody-dependent cell-mediated cytotoxicity

Fig. 1

3G3 bound to the membrane CD38 to kill Raji cells by ADCC. a ELISA analysis of 3G3 to bind coated CD38. 3G3 bound to CD38 well on a dose-dependent manner; b and c 3G3 bound to extracellular CD38 on Raji cells (b) on a dose-dependent manner (c). Human IgG (polyclonal) was set as negative control; d ADCC function of 3G3 in Raji cells on a dose dependent manner with the EC50 value of ~ 5 ng/mL

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BMC Biotechnology

ISSN: 1472-6750

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