Skip to main content
Fig. 2 | BMC Biotechnology

Fig. 2

From: Mucosal delivery of Lactococcus lactis carrying an anti-TNF scFv expression vector ameliorates experimental colitis in mice

Fig. 2

Histopathological score and histopathology of colonic tissue. a Histopathological score was determined from colon samples that were photographed in paraffin sections by H&E staining of a representative distal colon from each group. b Representative photos from distal colon tissue of a mouse from each experimental group are shown: Star ulceration; black arrow depletion of goblet cells; white arrow intestinal wall with intact mucosa and discrete inflammatory infiltrate. Experimental groups: NC, negative control group; DSS, DSS group; LL-F, L. lactis MG1363 FnBPA+ group and LL-FT, L. lactis MG1363 FnBPA+ (pValac::anti-TNFα) group. Data are expressed as the means ± SEM from an experiment using 4–5 animals per group and representative of three independent experiments. Statistical analysis was performed using the Mann-Whitney test; * p < 0.05 and ** p < 0.01

Back to article page

BMC Biotechnology

ISSN: 1472-6750

Contact us