TY - JOUR AU - Schatz, D. G. AU - Ji, Y. PY - 2011 DA - 2011// TI - Recombination centres and the orchestration of V(D)J recombination JO - Nat Rev Immunol VL - 11 UR - https://doi.org/10.1038/nri2941 DO - 10.1038/nri2941 ID - Schatz2011 ER - TY - JOUR AU - Martin, A. AU - Scharff, M. D. PY - 2002 DA - 2002// TI - Somatic hypermutation of the AID transgene in B and non-B cells JO - Proc Natl Acad Sci U S A VL - 99 UR - https://doi.org/10.1073/pnas.192442899 DO - 10.1073/pnas.192442899 ID - Martin2002 ER - TY - JOUR AU - Muramatsu, M. AU - Kinoshita, K. AU - Fagarasan, S. AU - Yamada, S. AU - Shinkai, Y. AU - Honjo, T. PY - 2000 DA - 2000// TI - Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme JO - Cell VL - 102 UR - https://doi.org/10.1016/S0092-8674(00)00078-7 DO - 10.1016/S0092-8674(00)00078-7 ID - Muramatsu2000 ER - TY - JOUR AU - Williams, S. C. AU - Frippiat, J. P. AU - Tomlinson, I. M. AU - Ignatovich, O. AU - Lefranc, M. P. AU - Winter, G. PY - 1996 DA - 1996// TI - Sequence and evolution of the human germline V lambda repertoire JO - J Mol Biol VL - 264 UR - https://doi.org/10.1006/jmbi.1996.0636 DO - 10.1006/jmbi.1996.0636 ID - Williams1996 ER - TY - JOUR AU - Calis, J. J. AU - Rosenberg, B. R. PY - 2014 DA - 2014// TI - Characterizing immune repertoires by high throughput sequencing: strategies and applications JO - Trends Immunol VL - 35 UR - https://doi.org/10.1016/j.it.2014.09.004 DO - 10.1016/j.it.2014.09.004 ID - Calis2014 ER - TY - JOUR AU - Corti, D. AU - Langedijk, J. P. AU - Hinz, A. AU - Seaman, M. S. AU - Vanzetta, F. AU - Fernandez-Rodriguez, B. M. AU - Silacci, C. AU - Pinna, D. AU - Jarrossay, D. AU - Balla-Jhagjhoorsingh, S. PY - 2010 DA - 2010// TI - Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals JO - PLoS One VL - 5 UR - https://doi.org/10.1371/journal.pone.0008805 DO - 10.1371/journal.pone.0008805 ID - Corti2010 ER - TY - JOUR AU - Corti, D. AU - Voss, J. AU - Gamblin, S. J. AU - Codoni, G. AU - Macagno, A. AU - Jarrossay, D. AU - Vachieri, S. G. AU - Pinna, D. AU - Minola, A. AU - Vanzetta, F. PY - 2011 DA - 2011// TI - A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza a hemagglutinins JO - Science VL - 333 UR - https://doi.org/10.1126/science.1205669 DO - 10.1126/science.1205669 ID - Corti2011 ER - TY - STD TI - Devilder MC, Moyon M, Saulquin X, Gautreau-Rolland L. Generation of discriminative human monoclonal antibodies from rare antigen-specific B cells circulating in blood. J Vis Exp. 2018;(132). ID - ref8 ER - TY - JOUR AU - Franz, B. AU - May, K. F. AU - Dranoff, G. AU - Wucherpfennig, K. PY - 2011 DA - 2011// TI - Ex vivo characterization and isolation of rare memory B cells with antigen tetramers JO - Blood VL - 118 UR - https://doi.org/10.1182/blood-2011-03-341917 DO - 10.1182/blood-2011-03-341917 ID - Franz2011 ER - TY - JOUR AU - Ouisse, L. H. AU - Gautreau-Rolland, L. AU - Devilder, M. C. AU - Osborn, M. AU - Moyon, M. AU - Visentin, J. AU - Halary, F. AU - Bruggemann, M. AU - Buelow, R. AU - Anegon, I. PY - 2017 DA - 2017// TI - Antigen-specific single B cell sorting and expression-cloning from immunoglobulin humanized rats: a rapid and versatile method for the generation of high affinity and discriminative human monoclonal antibodies JO - BMC Biotechnol VL - 17 UR - https://doi.org/10.1186/s12896-016-0322-5 DO - 10.1186/s12896-016-0322-5 ID - Ouisse2017 ER - TY - JOUR AU - Hoogenboom, H. R. PY - 2005 DA - 2005// TI - Selecting and screening recombinant antibody libraries JO - Nat Biotechnol VL - 23 UR - https://doi.org/10.1038/nbt1126 DO - 10.1038/nbt1126 ID - Hoogenboom2005 ER - TY - JOUR AU - Akamatsu, Y. AU - Pakabunto, K. AU - Xu, Z. AU - Zhang, Y. AU - Tsurushita, N. PY - 2007 DA - 2007// TI - Whole IgG surface display on mammalian cells: application to isolation of neutralizing chicken monoclonal anti-IL-12 antibodies JO - J Immunol Methods VL - 327 UR - https://doi.org/10.1016/j.jim.2007.07.007 DO - 10.1016/j.jim.2007.07.007 ID - Akamatsu2007 ER - TY - JOUR AU - Al-Qaisi, T. S. AU - Su, Y. C. AU - Roffler, S. R. PY - 2018 DA - 2018// TI - Transient AID expression for in situ mutagenesis with improved cellular fitness JO - Sci Rep VL - 8 UR - https://doi.org/10.1038/s41598-018-27717-2 DO - 10.1038/s41598-018-27717-2 ID - Al-Qaisi2018 ER - TY - JOUR AU - An, L. AU - Chen, C. AU - Luo, R. AU - Zhao, Y. AU - Hang, H. PY - 2018 DA - 2018// TI - Activation-induced cytidine deaminase aided in vitro antibody evolution JO - Methods Mol Biol VL - 1707 UR - https://doi.org/10.1007/978-1-4939-7474-0_1 DO - 10.1007/978-1-4939-7474-0_1 ID - An2018 ER - TY - JOUR AU - Bowers, P. M. AU - Horlick, R. A. AU - Neben, T. Y. AU - Toobian, R. M. AU - Tomlinson, G. L. AU - Dalton, J. L. AU - Jones, H. A. AU - Chen, A. AU - Altobell, L. AU - Zhang, X. PY - 2011 DA - 2011// TI - Coupling mammalian cell surface display with somatic hypermutation for the discovery and maturation of human antibodies JO - Proc Natl Acad Sci U S A VL - 108 UR - https://doi.org/10.1073/pnas.1114010108 DO - 10.1073/pnas.1114010108 ID - Bowers2011 ER - TY - JOUR AU - Ho, M. AU - Nagata, S. AU - Pastan, I. PY - 2006 DA - 2006// TI - Isolation of anti-CD22 Fv with high affinity by Fv display on human cells JO - Proc Natl Acad Sci U S A VL - 103 UR - https://doi.org/10.1073/pnas.0603653103 DO - 10.1073/pnas.0603653103 ID - Ho2006 ER - TY - JOUR AU - Ho, M. AU - Pastan, I. PY - 2009 DA - 2009// TI - Display and selection of scFv antibodies on HEK-293T cells JO - Methods Mol Biol VL - 562 UR - https://doi.org/10.1007/978-1-60327-302-2_8 DO - 10.1007/978-1-60327-302-2_8 ID - Ho2009 ER - TY - JOUR AU - McConnell, A. D. AU - Do, M. AU - Neben, T. Y. AU - Spasojevic, V. AU - MacLaren, J. AU - Chen, A. P. AU - Altobell, L. AU - Macomber, J. L. AU - Berkebile, A. D. AU - Horlick, R. A. PY - 2012 DA - 2012// TI - High affinity humanized antibodies without making hybridomas; immunization paired with mammalian cell display and in vitro somatic hypermutation JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0049458 DO - 10.1371/journal.pone.0049458 ID - McConnell2012 ER - TY - JOUR AU - Su, Y. C. AU - Al-Qaisi, T. S. AU - Tung, H. Y. AU - Cheng, T. L. AU - Chuang, K. H. AU - Chen, B. M. AU - Roffler, S. R. PY - 2014 DA - 2014// TI - Mimicking the germinal center reaction in hybridoma cells to isolate temperature-selective anti-PEG antibodies JO - mAbs VL - 6 UR - https://doi.org/10.4161/mabs.29124 DO - 10.4161/mabs.29124 ID - Su2014 ER - TY - JOUR AU - Wang, L. AU - Jackson, W. C. AU - Steinbach, P. A. AU - Tsien, R. Y. PY - 2004 DA - 2004// TI - Evolution of new nonantibody proteins via iterative somatic hypermutation JO - Proc Natl Acad Sci U S A VL - 101 UR - https://doi.org/10.1073/pnas.0407752101 DO - 10.1073/pnas.0407752101 ID - Wang2004 ER - TY - STD TI - Hwang JK, Alt FW, Yeap LS: Related Mechanisms of Antibody Somatic Hypermutation and Class Switch Recombination. Microbiol Spectr 2015, 3(1):MDNA3–0037-2014. ID - ref21 ER - TY - JOUR AU - Hess, G. T. AU - Tycko, J. AU - Yao, D. AU - Bassik, M. C. PY - 2017 DA - 2017// TI - Methods and applications of CRISPR-Mediated Base editing in eukaryotic genomes JO - Mol Cell VL - 68 UR - https://doi.org/10.1016/j.molcel.2017.09.029 DO - 10.1016/j.molcel.2017.09.029 ID - Hess2017 ER - TY - JOUR AU - Rees, H. A. AU - Liu, D. R. PY - 2018 DA - 2018// TI - Base editing: precision chemistry on the genome and transcriptome of living cells JO - Nat Rev Genet VL - 19 UR - https://doi.org/10.1038/s41576-018-0059-1 DO - 10.1038/s41576-018-0059-1 ID - Rees2018 ER - TY - JOUR AU - Hess, G. T. AU - Fresard, L. AU - Han, K. AU - Lee, C. H. AU - Li, A. AU - Cimprich, K. A. AU - Montgomery, S. B. AU - Bassik, M. C. PY - 2016 DA - 2016// TI - Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells JO - Nat Methods VL - 13 UR - https://doi.org/10.1038/nmeth.4038 DO - 10.1038/nmeth.4038 ID - Hess2016 ER - TY - JOUR AU - Yates, J. L. AU - Warren, N. AU - Sugden, B. PY - 1985 DA - 1985// TI - Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells JO - Nature VL - 313 UR - https://doi.org/10.1038/313812a0 DO - 10.1038/313812a0 ID - Yates1985 ER - TY - JOUR AU - Cumbers, S. J. AU - Williams, G. T. AU - Davies, S. L. AU - Grenfell, R. L. AU - Takeda, S. AU - Batista, F. D. AU - Sale, J. E. AU - Neuberger, M. S. PY - 2002 DA - 2002// TI - Generation and iterative affinity maturation of antibodies in vitro using hypermutating B-cell lines JO - Nat Biotechnol VL - 20 UR - https://doi.org/10.1038/nbt752 DO - 10.1038/nbt752 ID - Cumbers2002 ER - TY - JOUR AU - Delker, R. K. AU - Fugmann, S. D. AU - Papavasiliou, F. N. PY - 2009 DA - 2009// TI - A coming-of-age story: activation-induced cytidine deaminase turns 10 JO - Nat Immunol VL - 10 UR - https://doi.org/10.1038/ni.1799 DO - 10.1038/ni.1799 ID - Delker2009 ER - TY - JOUR AU - Maul, R. W. AU - Gearhart, P. J. PY - 2010 DA - 2010// TI - AID and somatic hypermutation JO - Adv Immunol VL - 105 UR - https://doi.org/10.1016/S0065-2776(10)05006-6 DO - 10.1016/S0065-2776(10)05006-6 ID - Maul2010 ER - TY - JOUR AU - Seo, H. AU - Hashimoto, S. AU - Tsuchiya, K. AU - Lin, W. AU - Shibata, T. AU - Ohta, K. PY - 2006 DA - 2006// TI - An ex vivo method for rapid generation of monoclonal antibodies (ADLib system) JO - Nat Protoc VL - 1 UR - https://doi.org/10.1038/nprot.2006.248 DO - 10.1038/nprot.2006.248 ID - Seo2006 ER - TY - JOUR AU - Mason, D. M. AU - Weber, C. R. AU - Parola, C. AU - Meng, S. M. AU - Greiff, V. AU - Kelton, W. J. AU - Reddy, S. T. PY - 2018 DA - 2018// TI - High-throughput antibody engineering in mammalian cells by CRISPR/Cas9-mediated homology-directed mutagenesis JO - Nucleic Acids Res VL - 46 UR - https://doi.org/10.1093/nar/gky550 DO - 10.1093/nar/gky550 ID - Mason2018 ER - TY - JOUR AU - Tiller, K. E. AU - Chowdhury, R. AU - Li, T. AU - Ludwig, S. D. AU - Sen, S. AU - Maranas, C. D. AU - Tessier, P. M. PY - 2017 DA - 2017// TI - Facile affinity maturation of antibody variable domains using natural diversity mutagenesis JO - Front Immunol VL - 8 UR - https://doi.org/10.3389/fimmu.2017.00986 DO - 10.3389/fimmu.2017.00986 ID - Tiller2017 ER - TY - STD TI - Liu LD, Huang M, Dai P, Liu T, Fan S, Cheng X, Zhao Y, Yeap LS, Meng FL: Intrinsic nucleotide preference of Diversifying Base editors guides antibody ex vivo affinity maturation. Cell Rep 2018, 25(4):884–892 e883. ID - ref32 ER - TY - JOUR AU - Boder, E. T. AU - Midelfort, K. S. AU - Wittrup, K. D. PY - 2000 DA - 2000// TI - Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity JO - Proc Natl Acad Sci U S A VL - 97 UR - https://doi.org/10.1073/pnas.170297297 DO - 10.1073/pnas.170297297 ID - Boder2000 ER - TY - JOUR AU - Persson, H. AU - Kirik, U. AU - Thornqvist, L. AU - Greiff, L. AU - Levander, F. AU - Ohlin, M. PY - 2018 DA - 2018// TI - In vitro evolution of antibodies inspired by in vivo evolution JO - Front Immunol VL - 9 UR - https://doi.org/10.3389/fimmu.2018.01391 DO - 10.3389/fimmu.2018.01391 ID - Persson2018 ER - TY - JOUR AU - MacDonald, K. G. AU - Hoeppli, R. E. AU - Huang, Q. AU - Gillies, J. AU - Luciani, D. S. AU - Orban, P. C. AU - Broady, R. AU - Levings, M. K. PY - 2016 DA - 2016// TI - Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor JO - J Clin Invest VL - 126 UR - https://doi.org/10.1172/JCI82771 DO - 10.1172/JCI82771 ID - MacDonald2016 ER - TY - JOUR AU - Noyan, F. AU - Zimmermann, K. AU - Hardtke-Wolenski, M. AU - Knoefel, A. AU - Schulde, E. AU - Geffers, R. AU - Hust, M. AU - Huehn, J. AU - Galla, M. AU - Morgan, M. PY - 2017 DA - 2017// TI - Prevention of allograft rejection by use of regulatory T cells with an MHC-specific chimeric antigen receptor JO - Am J Transplant VL - 17 UR - https://doi.org/10.1111/ajt.14175 DO - 10.1111/ajt.14175 ID - Noyan2017 ER -