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Table 4 IC50 of each parent and plasmid addition strain and percent differences of tolerance relative to the parent strain

From: Characterizing active transportation mechanisms for free fatty acids and antibiotics in Synechocystis sp. PCC 6803

Treatment   SD100 SD100 pacrA SD100 pKan SD100 pacrB SD100 pSpec
 Amp IC50 955.2 ± 256 1315 ± 77 (ns) 1151 ± 82 (ns) 1109 ± 123 (ns) 658.6 ± 88.3
% diff from SD100 0% 27% 20% 16% −31%
 Cm IC50 2.290 ± 0.401 1.444 ± 0.114 1.390 ± 0.186 1.976 ± 0.734 (ns) 1.653 ± 0.205 (ns)
% diff from SD100 0% −59% −39% −14% −28%
 Ery IC50 0.358 ± 0.081 μg/mL 0.080 ± 0.003 0.072 ± 0.007 0.138 ± 0.080 (ns) 0.079 ± 0.005
% diff from SD100 0% −77% − 79% −61% −78%
Treatment   SD277 SD277 pacrA SD277 pKan SD277 pacrB SD277 pSpec
 Amp IC50 1570 ± 170 μg/mL 1117 ± 21 μg/mL 76.67 ± 28.5 μg/mL 118.2 ± 8.7 μg/mL 412.6 ± 34.8 μg/mL
% diff from SD277 0% −29% −95% −92% −74%
 Cm IC50 4.749 ± 1.043 μg/mL 1.833 ± 0.390 μg/mL 1.793 ± 0.430 μg/mL 1.984 ± 0.527 μg/mL 2.96 ± 0.4 μg/mL
% diff from SD277 0% −61% − 62% −58% −38%
 Ery IC50 0.427 ± 0.249 μg/mL 0.091 ± 0.034 μg/mL 0.149 ± 0.016 μg/mL 0.080 ± 0.008 μg/mL 0.055 ± 0.004 μg/mL
% diff from SD277 0% −79% −65% −81% −87%
  1. The basis for the comparison in this table were the parent strains, either SD100 or SD277, featured in the third column. Each derivative strain is significantly different from the parent strain unless otherwise noted with “(ns)”