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Fig. 3 | BMC Biotechnology

Fig. 3

From: The nicotine-degrading enzyme NicA2 reduces nicotine levels in blood, nicotine distribution to brain, and nicotine discrimination and reinforcement in rats

Fig. 3

Quenching of NicA2 activity in brain in vitro by MeOH. Addition of MeOH to brain homogenate containing NicA2 prevented the degradation of subsequently added nicotine. However, a 10 s delay in adding MeOH to brain containing nicotine and NicA2 was sufficient to allow substantial degradation of nicotine. *** p < 0.001 using two-tailed unpaired t tests with Welch’s correction. Mean ± SD, n = 6/group

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BMC Biotechnology

ISSN: 1472-6750

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