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Fig. 5 | BMC Biotechnology

Fig. 5

From: Tetanus toxin fragments and Bcl-2 fusion proteins: cytoprotection and retrograde axonal migration

Fig. 5

Immunohistochemical observations of brain stems from B6CJ mice injected with fusion proteins. Sagittal section of the brain stem (a: Klüver-Barrera staining) was immunohistochemically stained using anti 6 × His antibody (b and d) or anti-Bcl-2 antibody (c and e). Fusion proteins were injected into the tongue muscle of mice and were seen to accumulate and localize in hypoglossal neurons (XII). Bcl2-hTTC reacted with both 6 × His (b) and Bcl-2 (d) antibodies, whereas TTC only reacted with the anti-6 × His antibody (c). Scale bar = 100 μm

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