Fig. 2
From: FGF23C-tail improves diabetic nephropathy by attenuating renal fibrosis and inflammation
FGF23C-tail treatment strikingly improved renal glomerular lesions in db/db Mice. a H & E staining of renal tissues; b PAS staining (indicating tubular injury and mesangial expansion; c-d Immunochemistry for NPHS2 and WT1, two biomarkers of podocytes; e Electron microscope images to observe the morphology of podocytes. Original magnification ×10000; f Mesangial matrix index statistically obtained from Panel B; g-h Semi-quantitative analysis for the NPHS2 and WT1-positive area; i-j Mean GBM thickness and podocyte effacement were semi-quantitatively analyzed based on Panel e