Table 2 Differential collagen neoepitope abundances between tendon tissue-engineered constructs derived from young and old donors
From: Donor age affects proteome composition of tenocyte-derived engineered tendon
Protein | Accession Number | Neopeptide Sequence | Previous Amino Acid | Following Amino Acid | Abundance Higher in Young or Old | Fold Change | p value |
|---|---|---|---|---|---|---|---|
Collagen type I alpha 1 chain | F7D939 | PQGPAGPAGPIGPVGAR | A | G | Old | 0.7 | 0.008 |
Collagen type I alpha 2 chain | F6RTH9 | GEAGAAGPAGPAGPRG | R | S | Old | 0.6 | 0.045 |
AGPVGAVGAPGPHGPVGPTGK | N | H | Old | 2.0 | 0.001 | ||
NGLQGLPGLAGQHGDQGAPGSVGPAGPR | H | G | Old | 2.7 | 0.018 | ||
Collagen type XII alpha 1 chain | F6QD89 | AIYPDESESDDLIGSERTPR | T | L | Old | 5.4 | 0.001 |
LEQLIPDTPYSVNIVAL | R | Y | Old | 11.9 | 0.002 | ||
LVQYSR | S | D | Young | 3.1 | 0.021 |