A new approach for detecting adventitious viruses shows Sf-rhabdovirus-negative Sf-RVN cells are suitable for safe biologicals production

Table 5 Summary of EVEs in Sf-RVN cells

EVE	Highest BLASTN E value	Highest TBLASTX E value	Length (bps)	Nonsense/rameshift mutations	RPKM	Reads mapped
Maraba virus L-like	6e-39	2e-59	493	1 / 1	0	0
Orinoco virus L-like	4.5 ^a	3e-42	280	0 / 1	571	105
Taï virus N-like	3.2 ^a	2e-22	534	0 / 0	29 × 10³	13,355
Pararge aegeria rhabdovirus N-like	0.69 ^a	7e-17	540	4 / 0	0	0
Shuangao insect virus 3 G-like	0.67 ^a	4e-36	1551	0 / 0	5.6	6
Sf-rhabdovirus N-like			1503	0 / 0	4.0	4
Sf-rhabdovirus P-like			1137	0 / 0	19	14
Sf-rhabdovirus G-like			1131	0 / 0	2.8	2
Sf-rhabdovirus L-like			1259	0 / 0	12	10

ISSN: 1472-6750