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Fig. 5 | BMC Biotechnology

Fig. 5

From: RETRACTED ARTICLE: DNA methylome profiling at single-base resolution through bisulfite sequencing of 5mC-immunoprecipitated DNA

Fig. 5

The methylation levels of MB-seq and MRB-seq in gene-associated regions. a Average methylation level of CpG in gene-associated regions using MB-seq and MRB-seq. Gene structure is divided into seven different functional regions and shown on x-axis. The y-axis is the average density of methylation sites in a 200 bp window. The green vertical line shows the mean location of the transcription start sites (TSS). b Average methylation level of CHG in gene-associated regions from MB-seq and MRB-seq. c Average methylation level of CHH in gene-associated regions from MB-seq and MRB-seq. MB-seq and MRB-seq clearly reflect the pattern of methylation level across different functional regions because of the enrichment of methylated non-CpG fragments. d The concordance and difference of CpG sites between MB-seq and BS-seq. e On the genome-wide level, and (f) CpG island-only level, the CpG sites covered solely in the BS-seq dataset were derived from low methylation level

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