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Table 1 Summary of computational annotations and reported topologies of known membrane and soluble proteins

From: A split ubiquitin system to reveal topology and released peptides of membrane proteins

 

WKS1

VKOR

PIP1;2

HPN

GPR3

GUS

Gene ID

KT834954.1

NM_119742.4

NM_130159

X07732.1

NM_005281

AJ298139.1

 

N

C

N

C

N

C

N

C

N

C

N

C

TMHMM

no TMHs

in

in

in

in

in

out

out

in

no TMHs

SOSUI

no TMHs

No results

No results

in

out

No results

no TMHs

TOPCONS

no TMHs

in

out

in

in

no TMHs

out

in

no TMHs

PHILIUS

no TMHs

in

out

in

in

no TMHs

in

in

no TMHs

HMMTOP

no TMHs

in

out

in

in

in

out

out

in

no TMHs

TMPRED

no TMHs

out

in

in

in

out

out

in

out

out

in

POLYPHOBIUS

no TMHs

in

out

out

in

in

out

out

in

no TMHs

HMM–TM

in

out

in

out

out

in

in

out

out

out

no TMHs

OCTOPUS

no TMHs

in

out

in

in

no TMHs

out

out

no TMHs

SUT

in

in

out

out

in

in

in

out

out

in

Soluble

Reference

  

out

out

in

in

in

out

out

in

Soluble

  1. N, N terminus. C, C terminus. Italic, different from experimental results. Computational predictions were done in versions of December 2016