Skip to main content
Fig. 2 | BMC Biotechnology

Fig. 2

From: Immobilisation of Delta-like 1 ligand for the scalable and controlled manufacture of hematopoietic progenitor cells in a stirred bioreactor

Fig. 2

Surface concentration of immobilised Delta-Like 1 can be controlled during particle synthesis. a Using the forward reaction pathway it is possible to control the presentation of DL1 by regulating the ratio of the heterobifunctionalised PEG molecule to the number of primary amine groups present in DL1 (n = 3). b Using the reverse synthetic pathway, DL1 immobilisation increases with increasing DL1 concentration in the second stage of the process (n = 3). c The use of increased PEG chain lengths within the heterofunctionalised biotin molecule results in a reduction in DL1 immobilisation using the reverse synthetic method (n = 3)

Back to article page

BMC Biotechnology

ISSN: 1472-6750

Contact us