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Table 2 pDNA production parameters

From: Heterogeneous oxygen availability affects the titer and topology but not the fidelity of plasmid DNA produced by Escherichia coli

Parameter

Units

Aerobic

Microaerobic

Oscilated

P

mg/L

4.9 ± 0.7

5.5 ± 1.1

3.8 ± 1.0

Y P/X

mg/g

1.3 ± 0.0

1.8 ± 0.3

1.6 ± 0.4

q P

mg/g h

0.63 ± 0.00

0.64 ± 0.04

0.55 ± 0.12

QP

mg/g h

0.17 ± 0.03

0.23 ± 0.02

0.25 ± 0.07

SCF

%

98 ± 0

97 ± 0

80 ± 6

  1. P pDNA titer at the end of cultivation, Y P/X average of the individual pDNA specific yield values during exponential growth, q P pDNA specific production rate, Q P pDNA global productivity, SCF average of the individual supercoiled pDNA fraction values during exponential growth. The data represent the average ± standard deviation of 3 independent experiments