A novel pyruvate kinase and its application in lactic acid production under oxygen deprivation in Corynebacterium glutamicum

Table 2 The production of organic acids by C. glutamicum strains in fed-batch fermentation^a

Strains	Glucose (mM/h)	Lactic acid (mM)	Lactic acid productivity (mM/h)	Yield^b (%)
Strains	Glucose (mM/h)	Lactic acid (mM)	Lactic acid productivity (mM/h)	Lactic acid	Succinic acid	Acetic acid	Total
WTΔpyk1	14.38 ± 0.27	454.04 ± 5.55	18.86 ± 0.21	65.60 ± 1.76	25.10 ± 0.40	3.20 ± 0.18	93.90 ± 2.34
WTΔpyk1/pXMJ19-pyk2	17.92 ± 0.50	669.03 ± 15.59	27.88 ± 0.65	77.82 ± 2.24	10.57 ± 0.24	7.70 ± 0.68	96.10 ± 3.16

^aThe cells were suspended to a final dry cell weight of 20 g/L in 3 L of CGXII medium with 100 mM bicarbonate. The data were derived from experiments performed at least in three times, and the error bars represent the standard deviations
^bThe yields were calculated as a percentage of the theoretical yield (100% represented 2 mol of lactic acid, succinic acid or acetic acid per 1 mol of glucose consumed)

ISSN: 1472-6750