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Table 1 Analytical parameters from RBA, bcELISA and CL-bELISA

From: Novel prokaryotic expression of thioredoxin-fused insulinoma associated protein tyrosine phosphatase 2 (IA-2), its characterization and immunodiagnostic application

Assay

RBA

bcELISA

CL-bELISA

Healthy control individuals (n)

37

23

39

Type 1 diabetic patients (n)

48

Median (SDs)

13.74

1.05

3.46

Range (SDs)

(-0.84)-57.08

(-2.76)-4.85

(-0.71)-111.20

Sensitivitya (%)

87.5

39.6

58.3

Specificityb

97.9

95.7

94.9

Analytical Sensitivityc (%)

-

40.5

59.5

  1. aPercentage of IA-2A positive patients from the total population studied
  2. b100 % minus the percentage of false positives
  3. cPercentage of patients RBA positive that were positive by each method