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Table 1 Analytical parameters from RBA, bcELISA and CL-bELISA

From: Novel prokaryotic expression of thioredoxin-fused insulinoma associated protein tyrosine phosphatase 2 (IA-2), its characterization and immunodiagnostic application

Assay RBA bcELISA CL-bELISA
Healthy control individuals (n) 37 23 39
Type 1 diabetic patients (n) 48
Median (SDs) 13.74 1.05 3.46
Range (SDs) (-0.84)-57.08 (-2.76)-4.85 (-0.71)-111.20
Sensitivitya (%) 87.5 39.6 58.3
Specificityb 97.9 95.7 94.9
Analytical Sensitivityc (%) - 40.5 59.5
  1. aPercentage of IA-2A positive patients from the total population studied
  2. b100 % minus the percentage of false positives
  3. cPercentage of patients RBA positive that were positive by each method