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Table 2 Parameters of succinate production by engineered E. coli strians during anaerobic fermentation

From: Targeted optimization of central carbon metabolism for engineering succinate production in Escherichia coli

Strains Growth rate (h−1) Titer (mM) Yield (mol/mol of glucose) Specific productivity (mmol gDCW−1 h−1) Productivity (mmol L−1 h−1)
Succinate Lactate Acetate Succinate Lactate Acetate Succinate Lactate Acetate Succinate Lactate Acetate
BKS10 0.071 ± 0.002 8.65 ± 0.73 12.06 ± 0.70 27.13 ± 2.56 0.31 ± 0.02 0.43 ± 0.02 0.98 ± 0.09 1.09 ± 0.06 1.47 ± 0.20 3.31 ± 0.13 0.12 ± 0.01 0.17 ± 0.01 0.39 ± 0.04
BKS11 0.052 ± 0.003** 25.51 ± 1.79** 7.82 ± 0.63** 23.52 ± 1.53 0.92 ± 0.06** 0.28 ± 0.02** 0.85 ± 0.05 3.96 ± 0.13** 1.18 ± 0.04* 3.54 ± 0.08 0.36 ± 0.03** 0.11 ± 0.01 0.34 ± 0.02
BKS15 0.043 ± 0.002* 30.12 ± 3.31 6.55 ± 0.33* 13.22 ± 1.64** 1.08 ± 0.11 0.24 ± 0.01* 0.48 ± 0.06** 5.89 ± 0.41** 1.20 ± 0.07 2.42 ± 0.19** 0.43 ± 0.05 0.09 ± 0.01 0.19 ± 0.02**
  1. The data are shown as mean values ± standard deviation (SD) of three replicates. Asterisks indicate p-values (**p < 0.01, *p < 0.05) in which BKS11 was compared to BKS10 and BKS15 was compared to BKS11