Skip to main content

Table 1 Analysis of cytokine released (pg/mL) in the supernatant of co-culture of APCs and T lymphocytes from NOD and BALB/c mice stimulated with medium, Con-A, or insulin

From: New strategy for testing efficacy of immunotherapeutic compounds for diabetes in vitro

Cytokine

Medium

Con-A

Insulin

 

NOD

BALB/C

NOD

BALB/C

NOD

BALB/C

IL-6

6234 ± 3217a

494 ± 377

9660 ± 2001

7632 ± 2104

13,881 ± 1138b

2762 ± 261

IFN-Î¥

96 ± 8a

4.5 ± 0.1

4754 ± 1725

3253 ± 3224

480 ± 204a

13 ± 11

IL-17

368 ± 27b

23.6 ± 22

680 ± 219a

28.8 ± 20.7

984 ± 34a

53 ± 26

IL-10

89 ± 12a

1.8 ± 0.5

758 ± 137b

50 ± 35

595 ± 118b

33 ± 21

  1. Data are reported as means ± SD for 3 separate experiments
  2. a P < 0.001
  3. b P < 0.05 when compared BALB/c to NOD mice (t-test)