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Fig. 7 | BMC Biotechnology

Fig. 7

From: Expression, purification and biological characterization of the extracellular domain of CD40 from Pichia pastoris

Fig. 7

CD40-N administration reduces the symptom of DSS-induced colitis. a Wild-type C57bl/c mice were injected on day 0, 2, 4, and 6 with either PBS or 200 μg of CD40-N and were given 2.75 % DSS. Body weight loss was recorded every day. The data represent the mean ± SEM (DSS with CD40-N: n = 6; DSS with PBS: n = 5; without DSS: n = 3). Student’s t-test was performed for statistical analysis. **p < 0.01, ***p < 0.001. b H&E staining of colon sections of mice at 7 day. The three pictures in the upper panel come from 3 DSS-treated mice with PBS treatment. The pictures in the lower panel show 3 DSS-treated mice with CD40-N treatment (magnification: 200×)

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