Fig. 2

Correlation between the productivity and recombinant gene copy numbers in the clones. The productivity and recombinant gene copy numbers of the clones are represented according to the ‘Beginning’ (weeks 1, 2) and at the ‘End’ (weeks 9, 10) of the 10-week study, as indicated. At the Beginning, when the clones were split for parallel growth without MTX in the media, there were no large differences in the productivity and copy numbers between the clones grown without and with MTX in the media. Due to high biological similarity of several (5) samples at the “Beginning”, some of the data are overlapping, and therefore not all 24 data points are visible