Table 4 Canonical combinations of the pre and post-selection sequences
A | Canonical combination (percentage of representation within the pre-selection sequences) | |
|---|---|---|
CDRs H1-H2 | CDRs L1-L2-L3 | |
Library 1 | 1-1 (97.3) | 6-1-X (51.3) |
2-4 (1) | 2-1-5 (11.2) | |
1-4 (1) | 6-1-5 (11.2) | |
2-1-X (10) | ||
Library 2 | 1-1 (94.8) | 6-1-X (46.7) |
2-1 (2.6) | 6-1-5 (20) | |
3-1 (1.3) | 5-1-X (16.6) | |
5-1-4 (−) | ||
Library 3 | 1-1 (100) | 6-1-X (45.3) |
5-1-X (14.7) | ||
2-1-X (17.7) | ||
5-1-5 (5.26) | ||
B | Canonical combination (percentage of representation within the post-selection clones) | |
CDRs H1-H2 | CDRs L1-L2-L3 | |
Library 1 | 1-1 (100) | 6-1-5 (88.9) |
2-1-X (11.1) | ||
Library 2 | 1-1 (100) | 6-1-X (25) |
5-1-4 (50) | ||
5-1-X (25) | ||
Library 3 | 1-1 (100) | 5-1-5 (100) |