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Fig. 2 | BMC Biotechnology

Fig. 2

From: Defining the complementarities between antibodies and haptens to refine our understanding and aid the prediction of a successful binding interaction

Fig. 2

The effect of amino acids within CDR H2 on the predicted positioning of CDRs H3 and L3. Amino acid positions H53 (red), H58 (yellow), and H59 (magentas) in clones a HSL1, b HSL2, c SQA A5, d SQA B3, e POR B11, f POR A7, g COP H3, and h COP A8. Position H53 has a profound effect on the orientation of CDR H3 (green), whilst positions H58 and H59 influence CDR L3 (blue) orientation. These homology images of the post-selection clones were constructed utilizing SWISS-MODEL workplace. The structures were viewed by PyMOL 1.3 (academic version)

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BMC Biotechnology

ISSN: 1472-6750

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