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Table 2 Human germline genes closer to the genes coding for the 24 scFvs with affinities better than 10 nM

From: Isolation of nanomolar scFvs of non-human primate origin, cross-neutralizing botulinum neurotoxins A1 and A2 by targeting their heavy chain

  Heavy chain Light chain
Clone name V D J V J
A1HC3 IGHV3-49*03 IGHD4-23*01 IGHJ4*02 IGKV1D-13*01 IGKJ3*01
A1HC6 IGHV3-21*04 IGHD4-17*01 IGHJ5*02 IGKV3-7*02 IGKJ3*01
A1HC7 IGHV3-49*03 IGHD4-23*01 IGHJ4*02 IGKV1-39*01 IGKJ4*01
A1HC17 IGHV5-51*01 IGHD6-19*01 IGHJ5*02 IGKV3-11*01 IGKJ3*01
A1HC26 IGHV3-49*03 IGHD4-23*01 IGHJ4*02 IGKV1-17*01 IGKJ4*01
A1HC31 IGHV3-49*03 IGHD4-23*01 IGHJ4*02 IGKV1-27*01 IGKJ2*03
A1HC32 IGHV5-a*04 IGHD1-26*01 IGHJ5*02 IGKV1-13*02 IGKJ1*01
A1HC33 IGHV3-49*03 IGHD4-23*01 IGHJ4*02 IGKV1-13*02 IGKJ4*01
A1HC34 IGHV3-49*03 IGHD4-23*01 IGHJ4*02 IGKV1-16*01 IGKJ4*01
A1HC38 IGHV5-a*04 IGHD1-26*01 IGHJ5*02 IGKV1-39*01 IGKJ3*01
A1HC39 IGHV3-49*03 IGHD4-23*01 IGHJ4*02 IGKV1-16*01 IGKJ4*01
A1HC43 IGHV1-69*04 IGHD3-22*01 IGHJ6*02 IGKV1-27*01 IGKJ3*01
A1HC45 IGHV3-49*03 IGHD4-23*01 IGHJ4*02 IGKV1-16*01 IGKJ4*01
A1HC47 IGHV3-49*03 IGHD4-23*01 IGHJ4*02 IGKV1-39*01 IGKJ4*01
A1HC49 IGHV3-49*03 IGHD4-23*01 IGHJ4*02 IGKV1-16*01 IGKJ2*01
A1HC58 IGHV3-49*03 IGHD4-23*01 IGHJ4*02 IGKV3-20*01 IGKJ3*01
A1HC62 IGHV5-51*01 IGHD5-12*01 IGHJ2*01 IGKV1-17*01 IGKJ4*01
A1HC64 IGHV3-49*03 IGHD4-23*01 IGHJ4*02 IGKV1-9*01 IGKJ2*03
A1HC65 IGHV3-71*01 IGHD4-23*01 IGHJ4*02 IGKV1-9*01 IGKJ1*01
A1HC67 IGHV1-69*04 IGHD2-15*01 IGHJ6*02 IGKV1-17*01 IGKJ2*01
A1HC68 IGHV3-49*03 IGHD4-23*01 IGHJ4*02 IGKV1-39*01 IGKJ4*01
A1HC74 IGHV1-69*04 IGHD2-15*01 IGHJ6*02 IGKV1-17*01 IGKJ2*03
A1HC80 IGHV3-49*03 IGHD4-23*01 IGHJ4*02 IGKV1-39*01 IGKJ3*01
A1HC81 IGHV3-49*03 IGHD4-23*01 IGHJ4*02 IGKV1-16*01 IGKJ4*01
  1. Human germline genes closer to the genes coding for the 24 best scFvs were retrieved using IMGT/V-QUEST. The scFvs in bold were of particular interest for this study