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Table 1 List of the 24 scFvs with affinities better than 10 nM

From: Isolation of nanomolar scFvs of non-human primate origin, cross-neutralizing botulinum neurotoxins A1 and A2 by targeting their heavy chain

Clone name Affinity (nM) Clone name Affinity (nM)
A1HC49 1.3 A1HC68 3.3
A1HC7 1.4 A1HC81 3.3
A1HC31 1.5 A1HC65 4
A1HC80 1.6 A1HC17 4.79
A1HC38 1.9 A1HC39 5
A1HC6 2.2 A1HC43 5
A1HC74 2.3 A1HC58 5
A1HC32 2.6 A1HC64 5
A1HC47 2.6 A1HC34 5.1
A1HC67 3.1 A1HC62 5.1
A1HC26 3.2 A1HC45 5.25
A1HC33 3.3 A1HC3 6.3
  1. Affinities were determined by surface plasmon resonance. The scFv were run in flux in a sensor chips coated with BoNT/A1. The scFvs in bold were of particular interest for this study