Skip to main content

Table 2 Antimicrobial (MIC) and hemolytic (MHC) activities of A20L

From: Prokaryotic expression and mechanism of action of α-helical antimicrobial peptide A20L using fusion tags

Peptide MIC MHC (μg/ml) TIb
Escherichia Coli Pseudomonas aeruginosa Staphylococcus aureus Bacillus subtilis GMa
ATCC25922 ATCC27853 ATCC25923 ATCC6633
A20L 2.67 7.33 21.33 5.33 6.87 213.33 31.05
  1. aGM denotes the geometric mean of the MIC values from all four microbial strains tested
  2. bTherapeutic index (TI) = MHC (μg/ml)/geometric mean of MIC (μg/ml)