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Table 2 Antimicrobial (MIC) and hemolytic (MHC) activities of A20L

From: Prokaryotic expression and mechanism of action of α-helical antimicrobial peptide A20L using fusion tags

Peptide

MIC

MHC (μg/ml)

TIb

(μg/ml)

Escherichia Coli

Pseudomonas aeruginosa

Staphylococcus aureus

Bacillus subtilis

GMa

ATCC25922

ATCC27853

ATCC25923

ATCC6633

A20L

2.67

7.33

21.33

5.33

6.87

213.33

31.05

  1. aGM denotes the geometric mean of the MIC values from all four microbial strains tested
  2. bTherapeutic index (TI) = MHC (μg/ml)/geometric mean of MIC (μg/ml)