Fig. 6
From: Active immunization with Tocilizumab mimotopes induces specific immune responses
Immunofluorescence staining of IL-6R expressed in Hela, U-937 and Jurkat cell line. Cells were incubated with Tocilizumab and pooled serum followed by FITC-labeled secondary antibodies where the nuclei were stained with DAPI. Cells were visualized with a fluorescence microscope. a Tocilizumab, (b) sera from mice immunized with 4A220-KLH, (c) sera from mice immunized with 4A124-KLH, (d) sera from mice immunized with 4A125-KLH, (e) sera from mice immunized with 4A126-KLH, (f) sera from mice immunized with the control peptide-KLH, (g) sera from mice immunized with KLH alone