Fig. 2From: Active immunization with Tocilizumab mimotopes induces specific immune responsesIsolated phage clones can mimic the original antigen. To demonstrate mimicry between the peptides and the original antigen, three independently phage competitive binding assay were then performed. a In Set one, rIL-6R could displace a large amount of bound phage from the Tocilizumab by using titration. b In Set two, the phage binding rate of all phage mimics decreased significantly after we added rIL-6R to compete with the binding of phage particles to Tocilizumab by using ELISA. c In Set three, the phage competitive rate of all phage mimics increased significantly after we added phage particles to compete with the binding of Tocilizumab to rIL-6R using ELISA (mean ± SD, *, P < 0.05; **, P < 0.005)Back to article page