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Table 2 Affinity determination by SPR

From: Structural differences of amyloid-β fibrils revealed by antibodies from phage display

  K D [M] on Aβ42 antigen
Antibody Monomers ( X 2 ) Protofibrils ( X 2 ) Fibrils ( X 2 )
PaD97-D6 2.3 × 10−6 (4.9%) 4.2 × 10−6 (2.4%) 9.1 × 10−7 (2.3%)
PaD172-F12 9.4 × 10−7 (2.4%) 1.5 × 10−6 (1.7%) 9.2 × 10−7 (2.4%)
PaD213-A5 No binding No binding 3.7 × 10−6 (1.1%)
PaD233-E5 1.0 × 10−8 (6.6%) 3.6 × 10−6 (1.4%) 1.2 × 10−6 (1.4%)
PaD236-H2 3.5 × 10−7 (2.5%) 5.8 × 10−7 (1.9%) 6.2 × 10−7 (5.7%)
  1. Chi2 (Χ 2) values are indicated in brackets.