Figure 6

Whole-cell MALDI-TOF can monitor immune activation events. Vent diagrams depicting for A) Pan-monocytes or B) CD16+ monocytes, m/z peak intensities significantly different between the detailed culture conditions (two-way ANOVA statistical analysis, p < 0.001). C) Smoothed mass spectra quadruplicates and respective scatter-plot of quadruplicate’s averaged mass peak intensities from resting CD16⁺ monocytes (green overlay) and LPS-treated CD16⁺ monocytes (red overlay) highlighting m/z areas containing putative phosphorylation of m/z 11316.24 into m/z 11396.28 (two-way ANOVA with Bonferroni post-tests correction, *** p < 0.001).