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Figure 5 | BMC Biotechnology

Figure 5

From: Generation and analysis of the improved human HAL9/10 antibody phage display libraries

Figure 5

Two-dimensional heatmap illustrating VH–Vκ gene pairing frequencies in the unselected HAL10 library (uns.) and in the selected scFvs from the HAL10 library (s.). Frequency of all functional VH genes [46] and Vκ genes [48] are shown. Genes that are not confirmed to be functional, but were found in the library/were selected are marked in orange. Vκ6 genes are all classified as non-functional and not inclued in this overview. 466 antibodies of the initial library and 130 selected scFvs were analyzed. The percentual amounts of each germline gene are given separetely for VH (rightmost columns) and Vκ (bottom row).

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