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Table 3 Average intensity of inflammatory cells, necrosis, fibrosis, neovascularization, and fatty in silk sericin-releasing bacterial nanocellulose gel and the commercial available paper mask after subcutaneous implantation for 3, 7, 14, and 28 days

From: The characteristics of bacterial nanocellulose gel releasing silk sericin for facial treatment

 

3 days

7 days

14 days

28 days

 

B*

C**

B

C

B

C

B

C

PMN

4 †

2.25

4

1.75

3.25

1.75

3.25

1

Lymphocytes

1

2

2

2

2.75

2

2.5

1.75

Plasma cells

0

0

0

0

0

0

0

0

Macrophages

3

2.5

3

3

3

3

3

3

Giant cells

0

0.5

0

2

0.75

3

1

3

Necrosis

0

0

0

0

0

0

0

0

Fibrosis

4

2.75

4

3.25

4

4

4

3.5

Neovascularization

3

2.5

3

1.25

2.75

1.75

2

3

Fatty infiltrate

0

3

0

1

0

0.75

0

0.5

  1. *B: silk sericin-releasing bacterial nanocellulose gel.
  2. **C: commercial available paper mask.
  3. † Intensity 0–4: 0 = not observed, 1 = rare, 2 = minimal, 3 = heavily infiltrate, and 4 = packed infiltrate.