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Table 3 Average intensity of inflammatory cells, necrosis, fibrosis, neovascularization, and fatty in silk sericin-releasing bacterial nanocellulose gel and the commercial available paper mask after subcutaneous implantation for 3, 7, 14, and 28 days

From: The characteristics of bacterial nanocellulose gel releasing silk sericin for facial treatment

  3 days 7 days 14 days 28 days
  B* C** B C B C B C
PMN 4 † 2.25 4 1.75 3.25 1.75 3.25 1
Lymphocytes 1 2 2 2 2.75 2 2.5 1.75
Plasma cells 0 0 0 0 0 0 0 0
Macrophages 3 2.5 3 3 3 3 3 3
Giant cells 0 0.5 0 2 0.75 3 1 3
Necrosis 0 0 0 0 0 0 0 0
Fibrosis 4 2.75 4 3.25 4 4 4 3.5
Neovascularization 3 2.5 3 1.25 2.75 1.75 2 3
Fatty infiltrate 0 3 0 1 0 0.75 0 0.5
  1. *B: silk sericin-releasing bacterial nanocellulose gel.
  2. **C: commercial available paper mask.
  3. Intensity 0–4: 0 = not observed, 1 = rare, 2 = minimal, 3 = heavily infiltrate, and 4 = packed infiltrate.