Figure 2

Activity evaluation of Dll _A and Dll _B TALENs by SSA assay. TALEN plasmids and the corresponding reporter plasmid, TALEN plasmids and unrelated reporter plasmid, or the reporter plasmid without TALEN plasmids were transfected into HEK293T cells. After the luciferase assay, fold activation scores against the positive control ZFN (pSTL-ZFA36 with the corresponding reporter) [28] were calculated. Data are expressed as means ± SEM (n = 3).