TY - JOUR AU - Rana, Satiander AU - Bhat, Wajid Waheed AU - Dhar, Niha AU - Pandith, Shahzad A. AU - Razdan, Sumeer AU - Vishwakarma, Ram AU - Lattoo, Surrinder K. PY - 2014 DA - 2014/11/23 TI - Molecular characterization of two A-type P450s, WsCYP98A and WsCYP76A from Withania somnifera (L.) Dunal: expression analysis and withanolide accumulation in response to exogenous elicitations JO - BMC Biotechnology SP - 89 VL - 14 IS - 1 AB - Pharmacological investigations position withanolides as important bioactive molecules demanding their enhanced production. Therefore, one of the pivotal aims has been to gain knowledge about complete biosynthesis of withanolides in terms of enzymatic and regulatory genes of the pathway. However, the pathway remains elusive at the molecular level. P450s monooxygenases play a crucial role in secondary metabolism and predominantly help in functionalizing molecule core structures including withanolides. SN - 1472-6750 UR - https://doi.org/10.1186/s12896-014-0089-5 DO - 10.1186/s12896-014-0089-5 ID - Rana2014 ER -