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Table 3 Effect of TMSBOL addition on the bioreduction conducted in C4 MIM·PF6/buffer biphasic system

From: Using a water-immiscible ionic liquid to improve asymmetric reduction of 4-(trimethylsilyl)-3-butyn-2-one catalyzed by immobilized Candida parapsilosis CCTCC M203011 cells

Addition of
TMSBOL (mM)
V o
(μmol/min gcwm)
Yielda
(%)
e.e.b
(%)
0 2.18 89.6 >99
3 1.88 84.5 >99
6 1.67 78.1 >99
12 1.34 68.8 >99
24 0.75 33.7 >99
  1. Reaction conditions: 24 mM TMSB, C4MIM·PF6/TEA-HCl buffer (100 mM, pH 5.0) volume ratio of 1/4, 98 mM 2-propanol, 0.15 g/mL cell-loaded alginate beads, 30°C, 180 r/min.
  2. aMaximum yield.
  3. bProduct e.e.