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Figure 3 | BMC Biotechnology

Figure 3

From: Thermochemotherapy effect of nanosized As2O3/Fe3O4complex on experimental mouse tumors and its influence on the expression of CD44v6, VEGF-C and MMP-9

Figure 3

Morphological changes of xenograft tumors in nude mice treated by different methods. a. control group (sterile 0.9% [w/v] NaCl); b. As2O3 group (5 μM As2O3 dispersed in 0.9% [w/v] NaCl); c. Fe3O4 group (1 mg/mL of Fe3O4 magnetic nanoparticles dispersed in 0.9% [w/v] NaCl plus MFH); d. As2O3/Fe3O4 group (1 mg/mL of Fe3O4 and 5 μM As2O3 dispersed in 0.9% [w/v] NaCl plus MFH). The tumors become smaller in animals treated with protocols 'a' to 'd'. Compared with the control, each group showed significant reductions in tumor volume and mass (p < 0.05 for both).

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