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Table 2 Characterization of NT2 neurospheres cultured in a fully controlled bioreactor.

From: Integrating human stem cell expansion and neuronal differentiation in bioreactors

Neurospheres
Time of harvesting (day) 9 16 23
Duration of retinoic acid treatment (week) 1 2 3
Neurosphere size (μm) 150 ± 40 309 ± 94 458 ± 44
Differentiation efficiency 0.13 ± 0.06 17.2 ± 2.2 37.4 ± 0.9
  1. Neurosphere size and neuronal differentiation efficiency are expressed as mean ± SEM from n = 2 independent bioreactor experiments.