A comparative study of recombinant and native frutalin binding to human prostate tissues

Table 2 Statistical analysis of the binding intensity of native and recombinant frutalin in human prostate tissues

Frutalin/source	Histological diagnosis	Number of cases for each binding intensity*				Mann-Whitney U analysis
		0	+	++	+++	Mean Rank	P
Native (A. incisa)	Benign prostate hyperplasia	0 (0%)	4 (16%)	13 (52%)	8 (32%)	19.90	0.051^I
	Prostate carcinoma	0 (0%)	1 (5%)	7 (35%)	12 (60%)	26.88
Recombinant (P. pastoris)	Benign prostate hyperplasia	25 (100%)	0 (0%)	0 (0%)	0 (0%)	16.00	0.000^S
	Prostate carcinoma	6 (30%)	9 (45%)	4 (20%)	1 (5%)	31.75

*The binding intensity was converted numerically as: negative (0) = 0, low (+) = 1, moderate (++) = 2 and strong (+++) = 3; ^I Insignificant statistical result; ^S Significant statistical result.