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Figure 5 | BMC Biotechnology

Figure 5

From: Archaeosomes made of Halorubrum tebenquichensetotal polar lipids: a new source of adjuvancy

Figure 5

Humoral response to ARC-entrapped BSA. (A) Primary antibody response. Mice were immunized sc on days 0 and 21 with 25 μg of BSA alone, BSA adsorbed on Al2O3, BSA entrapped in TEB-BM and TEB-GC or empty TEB. Serum samples were collected on days 28 and 60, and ELISA assayed for anti-BSA antibody titers. (B) Long-term memory response to ARC-entrapped BSA. Mice were immunized sc on days 0 and 21 with 25 μg of BSA alone, BSA adsorbed on Al2O3 or BSA entrapped in ARC, and boosted on day 180 with 25 μg of BSA (without adjuvant). Serum samples were collected three weeks later and assayed for anti-BSA antibody titers. Values represent mean titers ± SEM. ANOVA, * p < 0.05, **p < 0.01.

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