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Figure 9 | BMC Biotechnology

Figure 9

From: Generation of an external guide sequence library for a reverse genetic screen in Caenorhabditis elegans

Figure 9

Complexes between candidate target mRNAs and EGS-35, EGS-35-D, EGS-83, EGS-83-D. (A, B) Complexes between a candidate target mRNA and EGS-35 (A) and EGS-35-D (B). The arrow indicates the RNase P cleavage site. EGS-35-D was derived from EGS-35 by introducing base-substitution mutations at three positions (highlighted by circles) of the T-loop. (C, D) Complexes between a candidate target mRNA and EGS-83 (C) and EGS-83-D (D). The arrow indicates the RNase P cleavage site. EGS-83-D was derived from EGS-83 by introducing base-substitution mutations at three positions (highlighted by circles) of the T-loop.

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