Table 1 Extent of primary amine acetylation as determined by 1H NMR spectroscopy.
From: Acetylation of PAMAM dendrimers for cellular delivery of siRNA
| Sample | (-CH3/-CH2-) ratio | Number of acetyl groups added | Percent of primary amine acetylation |
|---|---|---|---|
| Ac20 | 0.041 | 27 | 21.1 |
| Ac40 | 0.075 | 50 | 39.1 |
| Ac60 | 0.115 | 76 | 59.4 |
| Ac84 | 0.16 | 107 | 83.6 |