TY - JOUR AU - Daniell, Henry AU - Ruiz, Gricel AU - Denes, Bela AU - Sandberg, Laurence AU - Langridge, William PY - 2009 DA - 2009/04/03 TI - Optimization of codon composition and regulatory elements for expression of human insulin like growth factor-1 in transgenic chloroplasts and evaluation of structural identity and function JO - BMC Biotechnology SP - 33 VL - 9 IS - 1 AB - Transgenic chloroplasts are potential bioreactors for recombinant protein production, especially for achievement of high levels of protein expression and proper folding. Production of therapeutic proteins in leaves provides transgene containment by elimination of reproductive structures. Therefore, in this study, human Insulin like Growth Factor-1 is expressed in transgenic chloroplasts for evaluation of structural identity and function. SN - 1472-6750 UR - https://doi.org/10.1186/1472-6750-9-33 DO - 10.1186/1472-6750-9-33 ID - Daniell2009 ER -