Skip to main content

Table 2 Control of B. annulatus infestations in cattle vaccinated with the recombinant Ba86 and Bm86 preparations.

From: Vaccination with recombinant Boophilus annulatus Bm86 ortholog protein, Ba86, protects cattle against B. annulatus and B. microplus infestations

  Boophilus annulatus(Mission, TX strain)
  Percent reduction (vaccinated/control)b Ec
Experimental group a DT DW DO DF  
Ba86 (Israeli strain) 71%
(217 ± 128)*
8%
(285 ± 17)
22%
(89 ± 10)*
25%
(0.3 ± 0.1)*
83.0%
Bm86 (Gavac; Cuban Camcord strain) 95%
(34 ± 33)*
54%
(141 ± 59)*
66%
(39 ± 17)*
75%
(0.1 ± 0.1)*
99.6%
Bm86 (Mozambique strain) 99%
(4 ± 2)*
23%
(240 ± 62)
25%
(85 ± 24)*
50%
(0.2 ± 0.1)*
99.6%
Adjuvant/saline control 750 ± 127 310 ± 52 114 ± 8 0.4 ± 0.04 ---
  1. aCattle were randomly assigned to experimental groups (N = 5), vaccinated and challenged with B. microplus and B. annulatus larvae.
  2. bThe percent reduction was calculated with respect to the control group: DT, % reduction in tick infestation; DW, % reduction in tick weight; DO, % reduction in oviposition; DF, % reduction in egg fertility. In parenthesis are shown the average ± S.E. for adult female tick number, tick weight, oviposition and egg fertility and were compared by Student's t-test with unequal variance between vaccinated and control groups. (*P < 0.05).
  3. cVaccine efficacy (E) was calculated as 100 [l-(CRT × CR0 × CRF)], where CRT, CRO and CRF are the reduction in the number of adult female ticks, oviposition and egg fertility as compared to the control group, respectively.