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Table 1 Titer of viral batches

From: Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants

Vector

Functional titer

*108 TU/ml

Relative DNA titer *108 U/ml

CMV.SIN

3.0 ± 0.4

N/A

s2 × 250.CMV

1.2 ± 0.5

1.6 ± 0.05

d2 × 250.CMV

0.16 ± 0.05 *

0.62 ± 0.05

1.2 kb.CMV

0.49 ± 0.08 *

1.2 ± 0.3

EF1α.SIN

3.9 ± 0.9

N/A

d2 × 250.EF1α

0.14 ± 0.02 *

0.9 ± 0.2 *

  1. Functional and relative DNA titer of viral vectors (mean ± SEM). CMV.SIN and EF1α.SIN work as references for each group of vectors. By definition the relative DNA titers of the control vectors (CMV.SIN and EF1α.SIN) are identical to their respective functional titers. * denotes significant (P < 0.05) different titer compared to the vector's respective control.
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BMC Biotechnology

ISSN: 1472-6750

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