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Table 5 Solution of optimum condition

From: A modeling study by response surface methodology and artificial neural network on culture parameters optimization for thermostable lipase production from a newly isolated thermophilic Geobacillus sp. strain ARM

No. Growth temperature (°C) Medium volume (ml) Inoculum size (%) Agitation rate (rpm) Incubation period (h) Initial pH ANN predicted activity (Uml-1) Actual activity ± SD (Uml-1) RSM predicted activity (Uml-1)
1 52.3 50 1 0 24 5.8 0.47 0.47 ± 0.003 0.476
2 50 50 2 10 24 6 0.453 0.453 ± 0.002 0.458
3 48 50 1.4 0 33.6 5.8 0.44 0.445 ± 0.005 0.444
4 48 50 1.4 10 33.6 5.7 0.424 0.425 ± 0.003 0.43
5 48 50 1.4 20 33.6 5.8 0.423 0.423 ± 0.006 0.423
6 49 50 1 40 33.6 6 0.418 0.419 ± 0.002 0.411
7 48 50 1.5 20 33.6 5.8 0.412 0.413 ± 0.001 0.415
  1. ANN R2 = 0.989
  2. ANN AAD = 0.059%
  3. RSM R2 = 0.95
  4. RSM AAD = 0.078%