A modeling study by response surface methodology and artificial neural network on culture parameters optimization for thermostable lipase production from a newly isolated thermophilic Geobacillus sp. strain ARM

Table 2 ANOVA for joint test

Source	Sum of Squares	DF	Mean Square	F Value	Prob > F
Model	0.083	27	3.075E-003	1176.88	< 0.0001	significant
A	1.462E-004	1	1.462E-004	55.96	0.0007
B	4.418E-005	1	4.418E-005	16.91	0.0092
C	3.536E-003	1	3.536E-003	1353.65	<0.0001
D	2.278E-003	1	2.278E-003	872.01	<0.0001
E	1.625E-003	1	1.625E-003	621.82	<0.0001
F	0.000	1	0.000	0.000	1.0000
A ²	3.236E-004	1	3.236E-004	123.86	0.0001
B ²	2.173E-005	1	2.173E-005	8.32	0.0344
C ²	2.829E-005	1	2.829E-005	10.83	0.0217
D ²	2.322E-004	1	2.322E-004	88.89	0.0002
E ²	1.457E-004	1	1.457E-004	55.78	0.0007
F ²	3.089E-003	1	3.089E-003	1182.37	<0.0001
AB	5.105E-003	1	5.105E-003	1954.11	<0.0001
AC	3.499E-003	1	3.499E-003	1339.22	<0.0001
AD	2.252E-003	1	2.252E-003	862.12	<0.0001
AE	1.873E-003	1	1.873E-003	716.75	<0.0001
AF	2.059E-004	1	2.059E-004	78.82	0.0003
BC	5.826E-003	1	5.826E-003	2229.90	<0.0001
BE	4.489E-003	1	4.489E-003	1718.28	<0.0001
BF	2.346E-003	1	2.346E-003	898.14	<0.0001
CD	2.162E-005	1	2.162E-005	8.28	0.0347
CE	2.992E-003	1	2.992E-003	1145.30	<0.0001
CF	5.720E-005	1	5.720E-005	21.90	0.0054
DE	9.310E-004	1	9.310E-004	356.38	< 0.0001
DF	1.373E-003	1	1.373E-003	525.44	< 0.0001
EF	6.529E-003	1	6.529E-003	2499.00	< 0.0001
ADE	2.820E-003	1	2.820E-003	1079.53	< 0.0001
Residual	1.306E-005	5	2.613E-006
Lack of Fit	5.625E-007	1	5.625E-007	0.18	0.6932	not significant
Pure Error	1.250E-005	4	3.125E-006
Cor Total	0.083	32

ISSN: 1472-6750