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Table 1 Strain names and genotypes

From: Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid

Strains

Genotype

Plasmid

References

BY4742

MATαα his3Δ1 leu2Δ0 lys2Δ0 ura3Δ0

none

41

EPY224

MATαα his3Δ1 leu2Δ0 lys2Δ0 ura3Δ0 PGAL1-tHMGR PGAL1-upc2-1 erg9::PMET3-ERG9 PGAL1-tHMGR PGAL1-ERG20

pRS425-Leu::ADS

7

EPY300

MATαα his3Δ1 leu2Δ0 lys2Δ0 ura3Δ0 PGAL1-tHMGR PGAL1-upc2-1 erg9::PMET3-ERG9 PGAL1-tHMGR PGAL1-ERG20

none

7

EPY230

EPY300

pRS425-Leu2d::ADS

This study

EPY305

EPY300

pESC-Leu:: ADS/AMO/CPR

This study

EPY306

EPY300

pESC-Leu2d::ADS

This study

EPY307

EPY300

pESC-Leu2d:: ADS/AMO/CPR

This study

EPY309

EPY300

pESC-Leu2d:: ADS/AMO-KO/CPR

This study

EPY330

lys2Δ0 ura3Δ0 repaired EPY300

pESC-Leu2d:: ADS/AMO/CPR

This study

EPY338

lys2Δ0 ura3Δ0 repaired EPY300

pESC-Leu2d:: ADS/AMO-KO/CPR

This study