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Table 1 Strain names and genotypes

From: Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid

Strains Genotype Plasmid References
BY4742 MATαα his3Δ1 leu2Δ0 lys2Δ0 ura3Δ0 none 41
EPY224 MATαα his3Δ1 leu2Δ0 lys2Δ0 ura3Δ0 PGAL1-tHMGR PGAL1-upc2-1 erg9::PMET3-ERG9 PGAL1-tHMGR PGAL1-ERG20 pRS425-Leu::ADS 7
EPY300 MATαα his3Δ1 leu2Δ0 lys2Δ0 ura3Δ0 PGAL1-tHMGR PGAL1-upc2-1 erg9::PMET3-ERG9 PGAL1-tHMGR PGAL1-ERG20 none 7
EPY230 EPY300 pRS425-Leu2d::ADS This study
EPY305 EPY300 pESC-Leu:: ADS/AMO/CPR This study
EPY306 EPY300 pESC-Leu2d::ADS This study
EPY307 EPY300 pESC-Leu2d:: ADS/AMO/CPR This study
EPY309 EPY300 pESC-Leu2d:: ADS/AMO-KO/CPR This study
EPY330 lys2Δ0 ura3Δ0 repaired EPY300 pESC-Leu2d:: ADS/AMO/CPR This study
EPY338 lys2Δ0 ura3Δ0 repaired EPY300 pESC-Leu2d:: ADS/AMO-KO/CPR This study