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Figure 8 | BMC Biotechnology

Figure 8

From: Impact of point-mutations on the hybridization affinity of surface-bound DNA/DNA and RNA/DNA oligonucleotide-duplexes: Comparison of single base mismatches and base bulges

Figure 8

Boxplots show the hybridization signal deviations (from the mean profile) for the different insertion base types (A I , C I , G I , T I , A II , C II , G II , T II ), which are differentiated according to affiliation to bulge Group I/II . Data processing: raw intensity data; solution-background correction; subtraction of the mean profile yields the defect-type dependent contribution of the hybridization signal. The statistical analysis includes about 1000 hybridization signals from 12 different 20 to 25 mer probe sequence motifs.

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BMC Biotechnology

ISSN: 1472-6750

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