Table 2 The anticancer effect of HCPT-loaded nanoparticles in the treatment of xenografts
From: Hydroxycamptothecin-loaded nanoparticles enhance target drug delivery and anticancer effect
Lovo cells xenograft | Tca8113 cells xenograft | |||||
|---|---|---|---|---|---|---|
TDT (d) | IR (%) | TV(cm3) | TDT (d) | IR (%) | TV(cm3) | |
Blank control | 3.0 | 0 | 4.336 ± 0.485 | 3.5 | 0 | 3.888 ± 0.547 |
PEG-PBLG | 2.9 | 0 | 4.206 ± 0.308* | 3.6 | 0 | 3.944 ± 0.179* |
HCPT | 4.3 | 70.0% | 1.299 ± 0.082# | 4.5 | 59.8% | 1.564 ± 0.286# |
HCPT/PEG-PBLG | 4.9 | 83.8% | 0.701 ± 0.067#§ | 4.9 | 85.6% | 0.559 ± 0.062#§ |