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Table 2 Results of conventional HPRT targeting strategies in hTERT transfected fibroblasts

From: Gene targeting in adult rhesus macaque fibroblasts

Vector Promoter IRES Antibiotic Coloniesr/5 × 106 cells Targeting events
pMK HPRT INEO None Yes NEO 0 0
pMK HPRT IPURO None Yes PURO 0 0
pHPRT+/- PGK No NEO 282 0