Figure 1
From: Comparison of chicken 7SK and U6 RNA polymerase III promoters for short hairpin RNA expression
Promoter element sequence alignment of chicken, bovine and human 7SK promoters. The enhancer (DSE) of the chicken 7SK promoter contains OCT-1 and SPH motifs but no CACCC box. The basal promoter region features a PSE and TATA box with homology to consensus. Matches to the defined consensus sequences indicated at the top of the OCT-1 [21], SPH [12], PSE [20] and TATA sequences are shown in upper case. Nucleotides conserved between chicken and either bovine or human 7SK promoter elements are underlined. Nucleotide positions indicate the location (5' → 3') of each element in the promoter relative to the transcription start site (+1). Each dash mark between the OCT-1 and CACCC box and PSE and TATA box represents one nucleotide. Nucleotide abbreviations in consensus sequences are according to the International Union of Biochemistry convention for GENBANK.