TY - JOUR AU - Goh, Shan AU - Camattari, Andrea AU - Ng, Daniel AU - Song, Ruth AU - Madden, Kevin AU - Westpheling, Janet AU - Wong, Victor VT PY - 2007 DA - 2007/10/24 TI - An integrative expression vector for Actinosynnema pretiosum JO - BMC Biotechnology SP - 72 VL - 7 IS - 1 AB - The Actinomycete Actinosynnema pretiosum ssp. auranticum has commercial importance due to its production of ansamitocin P-3 (AP-3), a potent antitumor agent. One way to increase AP-3 production would be to constitutively express selected genes so as to relieve bottlenecks in the biosynthetic pathway; however, an integrative expression vector for A. pretiosum is lacking. The aim of this study was to construct a vector for heterologous gene expression in A. pretiosum. SN - 1472-6750 UR - https://doi.org/10.1186/1472-6750-7-72 DO - 10.1186/1472-6750-7-72 ID - Goh2007 ER -